Figure 4.

Pearson correlations on run distance (km) and delta insulin B/S ratios (µL/g). The correlation between run distance and brain insulin uptake was compared in whole brain (A and E), olfactory bulb (B and F), hypothalamus (C and G), and frontal cortex (D and H). Males are presented in the top row (A–D) and females are in the bottom row (E–H). B and F: olfactory bulb insulin levels significantly correlated with running distance in both males (P = 0.034) and females (P = 0.045). H: in females, there was also a correlation in the frontal cortex (P = 0.01). Distance run reported in means ± SE: males = 2.6 ± 0.7 km, females = 4.7 ± 1.2 km.