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. 2022 Jan 28;322(4):H537–H548. doi: 10.1152/ajpheart.00612.2021

Table 2.

Plasma proteins in MI day 3 plasma that predict survival and day 7 dilation and tracked with day 3 dilation

Zero-Order Correlation Coefficient (r) β SE P Value Adjusted R2
MI survival
 A2M −0.70* −6.81 × 10−8 3.22 × 10−8 0.034 Pseudo R2 0.66
 EAF1 −0.65* −1.12 × 10−8 5.70 × 10−9 0.049
D3 diastolic volume
 APOBEC2 −0.60* −2.23 × 10−7 4.88 × 10−8 <0.001 0.67
 RanBP2 −0.49* 4.76 × 10−9 1.62 × 10−9 0.011
 FMNL2 −0.58* −4.60 × 10−8 1.57 × 10−8 0.011
 CD40L −0.44* 5.94 × 10−8 2.07 × 10−8 0.012
 ASB17 −0.46* −2.14 × 10−7 8.46 × 10−8 0.024
 Vmn2r106 0.49* 1.23 × 10−7 6.73 × 10−8 0.089
D7 diastolic volume
 NUDCD3 −0.48* −2.37 × 10−6 5.19 × 10−7 <0.001 0.56
 KIF3C −0.47* 7.18 × 10−8 1.95 × 10−8 0.0016
 FMNL2 −0.51* −1.04 × 10−7 2.85 × 10−8 0.0017
 ATP6V0D1 −0.51* 1.22 × 10−6 4.11 × 10−7 0.0080
 C7 −0.43* −2.21 × 10−7 7.52 × 10−8 0.0084
 MYO1A −0.52* −8.02 × 10−7 3.22 × 10−7 0.022
 UBIAD1 −0.39* −1.29 × 10−7 5.45 × 10−8 0.029
 CEP131 −0.48* 5.47 × 10−8 3.13 × 10−8 0.096

Proteins that best predict MI survival and dilation were selected using automatic model selection. Proteins are ranked by P value. *P < 0.05 for the zero-order correlation coefficient. A2M, α2-macroglobulin; ASB17, ankyrin repeat and SOCS box protein 17; APOBEC2, C->U editing enzyme APOBEC 2; ATP6V0D1, V type proton ATPase subunit d; C7, complement component C7; CD40L, CD40 ligand; CEP131, centrosomal protein of 131 kDa; D3, day 3; D7, day 7; EAF1, ELL-associated factor 1; FMNL2, formin-like protein 2; KIF3C, kinesin-like protein KIF3C; MYO1A, unconventional myosin Ia; NUDCD3, nudC-domain-containing protein 3; RanBP2, E3 SUMO-protein ligase RanBP2; UBIAD1, ubiA prenyltransferase domain-containing protein 1; VMN2R106, vomeronasal receptor Vmn2r106.