Figure 10.

T-CD3 lymphocytes and CD68 macrophages count in the renal cortex and outer medulla in normotensive rats (NORMOT) (n = 7), and in HFD-fed hypertensive rats treated with vehicle (n = 14 to 15), empagliflozin (EMPA) (n = 8), praliciguat (PRL) (n = 9 or 10) or empagliflozin + praliciguat (EMPA+PRL) (n = 9 or 10). Values are shown as means ± SE. Differences between groups were assessed with the use of unpaired t test. ^aP < 0.05 vs. normotensive; ^bP < 0.05 vs. vehicle; ^cP < 0.05 vs. empagliflozin; and ^dP < 0.05 vs. praliciguat.