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. Author manuscript; available in PMC: 2022 Dec 1.
Published in final edited form as: Hypertension. 2021 Nov 1;78(6):1742–1749. doi: 10.1161/HYPERTENSIONAHA.121.18315

Table 3:

Number needed to treat with intensive blood pressure lowering to prevent one incident heart failure event and the number needed to harm with intensive blood pressure lowering to cause one incident serious adverse event

Predicted HF Risk Tertile NNT - Heart Failure 95% Confidence Interval NNH - SAE 95% Confidence Interval
Low HF Risk 1185 ----- 23 13, 109
Intermediate HF Risk 177 ----- 128 -----
High HF Risk 76 42, 416 46 -----

NNT=Number Needed to Treat; NNH=Number Needed to Harm; SAE=Serious Adverse Event; HF=Heart Failure.

Confidence intervals of non-significant NNT and NNH values not included.