Table 4.
Overview of copper oxide biocomposite films' studies published as food packaging applications.
| Polymer + CuONPs | CuONPs' particle size | Polymer + CuONPs' particle size | Cytotoxicity (cell line-IC50) | Antimicrobial activities' tested strains | Antioxidant activity (DPPH-ABTS | Study |
|---|---|---|---|---|---|---|
| CMC-CuO | 40–50 nm | 60–75 nm | Not reported | E. coli-S. aureus | Not reported | [147] |
| Chitosan-CuO | Not reported | 10–25 nm | Not reported | E. coli-S. aureus | Not reported | [148] |
| Chitosan | Not reported | Not reported | MCF-7 = 29.73 μg/mL | E. coli, K. aerogenes-S. aureus-S. pyogenes | DPPH = 92.55 μg/mL ABTS = 92.06 μg/mL | [56] |
| CuO | Crystal size: 22 nm | ------ | MCF-7 = 28.82 μg/mL | DPPH = 91.71 μg/mL ABTS = 91.05 μg/mL | ||
| Chitosan-CuO | — | Crystal size: 23 nm | MCF-7 = 24.22 μg/mL | DPPH = 90.03 μg/mL ABTS = 90.95 μg/mL | ||
| Neem Seed-CuO | — | Crystal size: 82 nm | MCF-7 = 93.83 μg/mL | DPPH = 88.03 μg/mL ABTS = 89.99 μg/mL | ||
| Chitosan-copper oxide-neem seed (CS-CuO-NS) | — | Crystal size: 35 nm | MCF-7 = 16.33 μg/mL | DPPH = 76.02 μg/mL ABTS = 88.53 μg/mL | ||
| Chitosan-copper oxide (CS–CuO) | 13–15 nm | 10–30 nm | A549 = 20 ± 0.50 μg/mL | Not reported | Not reported | [57] |
| Terminalia catappa leaf extract cellulose/CuO | 21–40 nm | 10–60 nm | Not reported | E. coli | Not reported | [201] |
| CuO-bacterial cellulose composite | Not reported | 50–100 nm | Not reported | E. coli-S. aureus | Not reported | [58] |
| Chitosan-CuO | Not reported | 7 ± 2 nm | Not reported | E. coli-S. aureus | Not reported | [202] |
| Starch-based polyurethane/CuO nanocomposite | Not reported | 47.51 nm | Not reported | E. coli, S. aureus, P. aeruginosa, E. faecalis and C. albicans | Not reported | [203] |
| Carboxymethyl chitosan/CuO nanocomposites (CMCh/CuONPs) | Not reported | 20–50 nm | Not reported | E. coli-S. aureus | Not reported | [204] |
| BC-CuO | Sonochemical CuO crystal size: 43.52 nm | Sonochemical BC crystal size: 1.67 nm | Not reported | E. coli-S. aureus | Not reported | [59] |
| Precipitation CuO crystal size: 52.19 nm | Precipitation BC crystal size: 1.82 nm | |||||
| Cellulose gum and copper nanoparticles-based hydrogel (HCuNPs) | 7–12 nm | Not reported | HeLa cells = 45 μg/mL | K. pneumonia, E. coli, P. aeruginosa, S. aureus, P. vulgaris and P. mirabilis | Not reported | [205] |
| Chitosan-CuO | 50–60 nm | 58 nm | Not reported | Not reported | Not reported | [206] |
| Carrageenan and copper nanoparticles-based hydrogels and films | Not reported | 150–200 nm | Not reported | E. coli - L. monocytogenes | Not reported | [172] |
| Chitosan-CuNPs | 163 nm | 100–200 nm | Not reported | P. aphanidermatum-R. solani | Not reported | [207] |
| Cellulose-CuNPs | 20–80 nm | 100 nm | Not reported | E. coli-Bacillus.sp | Not reported | [208] |
| Sodium alginate (1%)-CuONPs (1 mM) | Not reported | Not reported | Not reported | S. aureus, E. coli, Salmonella sp., C. albicans, Trichoderma spp. | DPPH = 25%ABTS = 29% | [149] |
| Sodium alginate (3%)-CuONPs (1 mM) | DPPH = 33%ABTS = 30% | |||||
| Sodium alginate (3%)-CuONPs (5 mM) | DPPH = 38%ABTS = 20% | |||||
| CNW (0.5%)-SA (3%)-CuoNPS (5 mM) | DPPH = 46.55%ABTS = 35.46% | |||||
| Agar-CuO nanoparticles (AG-CuO) | 92 ± 15 nm | Not reported | Not reported | Not reported | Not reported | [209] |
| Chitosan-CuO | Not reported | Crystal size: 17 nm | Not reported | B. subtilis, P. aeruginosa, E. coli, P. notatum | Not reported | [210] |
| PLA/ZnO : Cu/Ag bionanocomposites | Not reported | 50–100 nm | Not reported | S. aureus, P. aeruginosa | Not reported | [160] |
| Cotton cellulose/copper nanoparticles (CuNP) | 28.9 nm | Not reported | Not reported | E. coli | Not reported | [161] |
| Cu nanoparticles/chitosan composite film | Not reported | 10.6 ± 1 nm | Not reported | S. aureus-Salmonella typhimurium | Not reported | [162] |
| Kefiran-CMC-CuONPs (0.5%) | 40 nm | Not reported | Not reported | E. coli-S. aureus | Not reported | [163] |
| Kefiran-CMC-CuONPs (1%) | ||||||
| Kefiran-CMC-CuONPs (2%) |