Table 1.
Features of the enrolled participants. Data represent the mean ± standard deviation, the median (25th, 75th percentile) or the number of participants (%) unless otherwise stated.
| Lean N=257 |
Overweight N=99 |
Obese N=138 |
|
|---|---|---|---|
| BMI percentile | 50.8 ± 24.5 | 90.6 ± 2.6 | 97.9 ± 1.5 |
| Age (years) | 11.9 ± 3.7 | 11.9 ± 3.5 | 11.6 ± 3.0 |
| Asthma duration (years) | 8.8 ± 4.5 | 8.9 ± 3.7 | 9.1 ± 3.8 |
| Males | 143 (55.6) | 57 (57.6) | 82 (59.4) |
| Hispanic ethnicity | 19 (7.4) | 5 (5.1) | 10 (7.2) |
| Race | |||
| White | 95 (37.0) | 32 (32.3) | 34 (24.6) |
| Black | 139 (54.1) | 58 (58.6) | 87 (63.0) |
| Other | 23 (9.0) | 9 (9.1) | 17 (12.3) |
| Parent with asthma | 135 (55.3) | 48 (50.0) | 88 (64.7) |
| College degree in household | 96 (37.4) | 40 (40.4) | 41 (29.7) |
| Tobacco smoke exposure | 35 (14.2) | 15 (15.5) | 26 (19.0) |
| Comorbid conditions (any in past year) | |||
| Sinusitis | 68 (26.5) | 35 (35.4) | 49 (35.5) |
| Pneumonia | 120 (46.7) | 53 (53.5) | 73 (52.9) |
| Gastroesophageal reflux | 56 (21.8) | 21 (21.2) | 44 (31.9)* |
| Asthma controller medications | |||
| Inhaled corticosteroid (any dose) | 242 (81.5) | 95 (79.8) | 135 (88.2) |
| Inhaled corticosteroid (high dose) | 139 (46.8) | 68 (57.1) | 95 (62.1)* |
| Long-acting beta agonist | 158 (53.2) | 74 (62.2) | 103 (67.3)* |
| Montelukast | 182 (61.3) | 73 (61.3) | 102 (66.7) |
| Omalizumab | 6 (2.0) | 3 (2.5) | 8 (5.2) |
| Self-reported asthma triggers | |||
| Walking or daily activity | 112 (43.6) | 47 (47.5) | 89 (64.5)*^ |
| Exercise or sports | 147 (57.2) | 61 (61.6) | 91 (65.9) |
| Respiratory infections | 222 (86.4) | 93 (93.9) | 133 (96.4)* |
| Reduction in inhaled corticosteroid dose | 103 (40.1) | 44 (44.4) | 65 (47.1) |
| Allergic sensitization features | |||
| Eczema | 139 (54.1) | 58 (58.6) | 89 (64.5)* |
| Positive aeroallergens (of 8 tested) | 3 (1, 7) | 3 (1, 9) | 5 (2, 7) |
| Blood eosinophil count (cells/microliter) | 281 (156, 492) | 245 (126, 481) | 308 (145, 490) |
| Serum IgE (kU/L) | 299 (92, 809) | 275 (69, 934) | 462 (146, 875) |
*
p<0.05 vs. lean asthma
^
p<0.05 vs. overweight asthma