Skip to main content
. Author manuscript; available in PMC: 2023 Apr 1.
Published in final edited form as: Biol Psychiatry. 2021 Oct 20;91(7):647–657. doi: 10.1016/j.biopsych.2021.10.008

Table 1.

Cohort Selection

Patients PCL Pairs
Overall Cohort
A How many patients had any diagnosis of PTSD between 10/1/99 and 9/30/19? 2,098,389 N/A
B How many of (A) had at least 1 PCL Score? 852,438 N/A
C How many of (B) had at least 1 additional PCL score within 30 to 365 days of the first? 353,847 6,158,258
D How many of (C) do not include overlapping PCL pairs within the same patient? 353,847 480,372
E How many of (D) had at least one concurrent drug trial lasting at least 28 days? 192,006 223,048
F How many of (E) met the criteria to be considered a case* or control**? 168,941 192,912

Sensitivity Analysis Cohorts
G How many of (F) did not coincide with any instance of EBT? 69,453 75,266
H How many of (F) had a baseline PCL score of 38 or higher and a PTSD diagnosis within 30 days of baseline? 119,372 134,289
I How many of (H) did not coincide with any instance of EBT? 44,400 47,778

PTSD=Posttraumatic Stress Disorder, PCL=PTSD Checklist, EBT=Evidence-Based Treatment for PTSD

*

Case: PCL improvement of 15 points or more

**

Control: PCL improvement of 7 points or less or PCL worsening