Table 1:
Physiological parameters.
| Group | Time Point | Body Weight (g) | Body Temperature (°C) | Head Temperature (°C) | pH | pCO2 (mmHg) | pO2 (mmHg) | MABP (mmHg) |
|---|---|---|---|---|---|---|---|---|
| ITD + vehicle (n=8) | Before | 352 ± 8 | 37.0 ± 0.0 | 36.8 ± 0.1 | 7.43 ± 0.02 | 38 ± 1 | 120 ± 4 | 97 ± 2 |
| During | 37.0 ± 0.0 | 36.6 ± 0.1 | 7.34 ± 0.02 | 50 ± 2 | 115 ± 5 | 50 ± 0 | ||
| After | 37.0 ± 0.0 | 36.8 ± 0.1 | 7.44 ± 0.01 | 35 ± 2 | 136 ± 8 | 101 ± 3 | ||
| ITD + RH + vehicle (n=7) | Before | 353 ± 9 | 37.0 ± 0.0 | 36.8 ± 0.1 | 7.47 ± 0.04 | 38 ± 1 | 118 ± 6 | 103 ± 6 |
| During | 36.9 ± 0.1 | 36.6 ± 0.1 | 7.34 ± 0.01 | 45 ± 2 | 118 ± 7 | 49 ± 1 | ||
| After | 37.0 ± 0.0 | 36.7 ± 0.1 | 7.43 ± 0.01 | 39 ± 1 | 115 ± 6 | 100 ± 7 | ||
| ITD + RH + PcTx1 (n=6) | Before | 339 ± 6 | 36.9 ± 0.1 | 36.4 ± 0.1 | 7.40 ± 0.02 | 37 ± 2 | 134 ± 8 | 103 ± 4 |
| During | 36.8 ± 0.1 | 36.5 ± 0.2 | 7.27 ± 0.02 | 53 ± 3 | 124 ± 6 | 49 ± 0 | ||
| After | 36.9 ± 0.1 | 36.5 ± 0.2 | 7.38 ± 0.02 | 36 ± 2 | 142 ± 9 | 113 ± 5 | ||
| ITD + RH + APETx2 (n=8) | Before | 353 ± 19 | 37.1 ± 0.1 | 36.6 ± 0.1 | 7.47 ± 0.01 | 37 ± 1 | 132 ± 9 | 103 ± 1 |
| During | 36.9 ± 0.1 | 36.5 ± 0.1 | 7.44 ± 0.01 | 34 ± 2*, † | 126 ± 8 | 49 ± 0 | ||
| After | 37.4 ± 0.1 | 36.9 ± 0.1 | 7.47 ± 0.01 | 34 ± 1 | 141 ± 5 | 113 ± 2 |
*
p<0.05 vs ITD + vehicle control.
†
p<0.05 vs ITD + RH + vehicle control.