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. Author manuscript; available in PMC: 2022 Sep 1.
Published in final edited form as: Cancer Discov. 2021 Mar 19;11(9):2216–2229. doi: 10.1158/2159-8290.CD-20-1052

Figure 2. Domain mapping of ZFTA-fusion driven nuclear translocation.

Figure 2.

A. Schematics of deletion (Δ)-mutant fusion proteins. B. Immunoblots probed with indicated antibodies of cytoplasmic and nuclear fractions of HA-tagged proteins in HEK293 cells. Vinculin (cytoplasmic) and Cre (nuclear) are loading controls. C. Percent of proteins localized in cytoplasm or nucleus. Average difference ± Standard Error (SE) and Mann-Whitney p-value (n=5), below. D. Schematics of deletion-mutant fusion proteins. E. Localization of enhanced (e)-GFP tagged proteins in live HEK293 cells (scale bar, 10μm).