TABLE 2.
Age effects on global brain volumes and AD‐relevant temporal‐parietal regions of interest
| Effects of age (P values) | ||||
|---|---|---|---|---|
| ROI | ROI type | Middle‐aged (8–16 yoa) | Older‐aged (> 16 yoa) | Entire sample (8–29 yoa) |
| Intracranial volume | Volume | .243 | .006 | .945 |
| Total brain volume | Volume | .201 | .005 | .407 |
| Total gray matter | Volume | .412 | .047 | <.001 |
| Cortical gray matter | Volume | .412 | .356 | .003 |
| Deep gray matter | Volume | .857 | .002 | <.001 |
| White matter | Volume | .064 | .098 | .052 |
| Cerebrospinal fluid | Volume | .331 | .438 | .005 |
| Angular gyrus | Thickness | .939 | .033 | .103 |
| Inferior temporal gyrus | Thickness | .220 | <.001 | .007 |
| Middle temporal gyrus | Thickness | .557 | .005 | .273 |
| Superior temporal gyrus | Thickness | .761 | <.001 | <.001 |
| Precuneus | Thickness | .917 | .786 | .014 |
| Fusiform gyrus | Thickness | .445 | <.001 | <.001 |
| Supramarginal gyrus | Thickness | .802 | .803 | .074 |
| Entorhinal cortex | Thickness | .337 | .178 | .876 |
| Parahippocampus | Thickness | .562 | .012 | .194 |
| Temporal‐parietal meta‐ROI | Thickness | .436 | <.001 | .001 |
P values relate to main effects of age. P values < .05 is shown in bold.
Abbreviations: AD, Alzheimer's disease; ROI, region of interest.