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. 2022 Mar 10;10:e12944. doi: 10.7717/peerj.12944

Table 1. The relationship between IER3 expression and clinicopathological arguments of HCC based on in-house IHC.

Clinicopathologic arguments Number IER3 expression R p-value
Tissue HCC 94 10.64 ± 2.08 0.725 <0.001
Non-HCC 127 6.50 ± 2.73
Age <60 171 8.03 ± 3.24 0.843 <0.001
≥60 50 9.04 ± 3.00
Gender Female 64 7.61 ± 3.67 –0.053 0.677
Male 157 8.52 ± 2.97
Pathologic grade I–II 63 10.73 ± 1.88 –0.164 0.353
III–IV 24 10.67 ± 2.55
Alcohol history No 54 9.37 ± 3.10 0.211 0.128
Yes 53 10.64 ± 2.21
Alpha-fetoprotein (AFP) <20 ng/mL 44 8.86 ± 3.30 –0.076 0.021
>20 ng/mL 62 10.77 ± 2.12

Notes.

HCC
hepatocellular carcinoma
IER3
immediate early response 3
IHC
immunohistochemistry
R
Pearson correlation coefficient