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. 2022 Mar 10;10:e12944. doi: 10.7717/peerj.12944

Table 3. The relationship between IER3 expression and clinicopathological arguments of HCC based on the TCGA database.

Clinicopathologic arguments Number IER3 expression R p- value
Age ≥60 232 10.79 ± 0.91 0.006 0.938
<60 191 8.16 ± 0.94
Gender Male 280 9.53 ± 1.61 0.075 0.389
Female 143 9.73 ± 1.61
Pathologic grade G1–G2 265 9.47 ± 1.61 0.18 0.027
G3–G4 150 9.82 ± 1.60
Pathologic stage I–II 288 9.56 ± 1.61 0.677 <0.001
III–IV 103 9.66 ± 1.65
New tumour event after initial treatment No 196 9.49 ± 1.50 0.995 <0.001
Yes 198 9.65 ± 1.68
Alcohol history No 275 9.58 ± 1.67 0.265 0.003
Yes 126 9.60 ± 1.59

Notes.

HCC
hepatocellular carcinoma
IER3
immediate early response 3
TCGA
The Cancer Genome Atlas
R
Pearson correlation coefficient