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. 2021 May 3;314(3):239–246. doi: 10.1007/s00403-021-02231-0

Table 1.

Levels of evidence by study

Level of evidence Total number of studies Included studies
1b 16 2, 3, 12, 13, 21, 25, 26, 27, 28, 30, 31, 36, 38, 39, 40, 41
2b 19 4, 5, 7a, 11, 15, 17, 18, 19, 22, 29, 32, 34, 35, 37, 42, 43, 44, 45, 47
4 3 7a, 9, 16

Level of study is determined by Oxford Centre for Evidence-based Medicine guidelines

aStudy 7 is included twice because it involved 2 phases of different study design