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. 2022 Feb 3;39(3):1417–1431. doi: 10.1007/s12325-021-02039-4

Table 1.

Demographics and preoperative characteristics (n = 125)

Mean ± SD (unless noted otherwise) Combined
iStent inject + Phaco
(81 eyes)
Standalone
iStent inject
(44 eyes)
Age (years) 72.7 ± 7.5 71.3 ± 10.5
Range (years) 54–86 40–88
Gender 56% male/44% female 52% male/48% female
Cup:disc ratio 0.74 ± 0.17 0.78 ± 0.18
VF MD − 6.6 ± 2.8 dB − 7.0 ± 3.5 dB
Retinal nerve fiber layer thickness (µm) 81.4 ± 12.3 82.1 ± 13.6
Race/ethnicity 100% non-Hispanic white 100% non-Hispanic white
Eyes with prior glaucoma procedures (%) 26 (32%) 22 (50%)
Prior glaucoma procedures 31 procedures in 26 eyes 35 procedures in 22 eyes
 Trabeculectomy 12 13
 CPC 10 14
 ALT/SLT 5 3
 Laser iridotomy 2 2
 Surgical iridectomy 1 0
 Single first-gen iStent 0 1
 XEN implantation 1 2
Type of glaucoma n (%) n (%)
 POAG 60 (74%) 38 (86%)
 PXG 15 (19%) 4 (9%)
 Combined-Mechanism 4 (5%) 1 (2%)
 Pigmentary 1 (1%) 0 (0%)
 Secondary (neovascular/CRVO) 1 (1%) 1 (2%)
Mean medicated IOP 22.6 ± 6.2 mmHg 25.3 ± 6.0 mmHg
Mean # medications 2.52 ± 1.06 2.98 ± 0.88
Medicated IOP (mmHg) n (%) n (%)
 ≤ 15 mmHg 1 (1%) 1 (2%)
 ≤ 18 mmHg 22 (27%) 4 (9%)
Medication burden n (%) n (%)
 Eyes med-free 1 (1%) 0 (0%)
 Eyes on 3–5 preop meds 44 (54%) 33 (75%)

IOP intraocular pressure, SD standard deviation, C:D cup:disc, VF MD visual field mean deviation, Preop preoperative, POAG primary open-angle glaucoma, PXG pseudoexfoliative glaucoma, CRVO central retinal vein occlusion, CPC cyclophotocoagulation, ALT argon laser trabeculoplasty, SLT selective laser trabeculoplasty; Med medication, Preop preoperative, Phaco phacoemulsification