Table 1.
General characteristics of the ONTIME-MT study population (n = 845)
| Total population | MTNR1B genotype | P value‡ | |||
|---|---|---|---|---|---|
| CC genotype | CG genotype | GG genotype | |||
| n (%) | 845 (100) | 423 (50) | 342 (40) | 80 (10) | — |
| Age, years | 38 ± 14 | 37 ± 14 | 39 ± 14 | 37 ± 15 | 0.192 |
| Sex, % female (n) | 71 (600) | 70 (295) | 71 (243) | 78 (62) | 0.375 |
| BMI, kg/m2 | 25.67 ± 4.69 | 25.94 ± 4.91 | 25.41 ± 4.36 | 25.40 ± 4.90 | 0.264 |
| Body fat, % | 28.93 ± 9.86 | 29.16 ± 9.87 | 28.74 ± 9.93 | 28.57 ± 9.64 | 0.794 |
| Obesity, % (n) | 17.8 (150) | 18.9 (80) | 15.8 (54) | 20 (16) | 0.468 |
| Habitual dinner timing, h | 2138 ± 0034 | 2138 ± 0033 | 2138 ± 0036 | 2135 ± 0032 | 0.803 |
| Habitual bedtime, h | 2432 ± 0057 | 2432 ± 0058 | 2433 ± 0059 | 2430 ± 0052 | 0.955 |
| Melatonin EE timing condition (pg/mL)*† | 22.76 ± 13.07 | 23.03 ± 12.72 | 21.91 ± 12.43 | 25.15 ± 17.18 | 0.246 |
| Melatonin LE timing condition (pg/mL)*† | 66.18 ± 44 | 65.9 ± 41.96 | 65.32 ± 47.4 | 71.47 ± 39.32 | 0.643 |
| Habitual dinner energy intake (kcal) | 434.42 ± 248.65 | 425.77 ± 238.08 | 434.76 ± 256.57 | 477.88 ± 266.12 | 0.234 |
| Habitual dinner carbohydrate intake (g) | 40.13 ± 23.33 | 39.47 ± 22.59 | 40.28 ± 23.95 | 42.93 ± 24.52 | 0.477 |
Data are mean ± SD unless otherwise indicated.
*
n = 588.
†
Mean of T0 and T120.
‡
ANOVA among three genotypes.