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. 2022 Mar 12;22:178. doi: 10.1186/s12888-022-03811-8

Table 3.

The association between relative expressions of VDR-associated genes and BD based on the results of Bayesian Quantile regression model. When the interaction effects were significant, subgroup analysis by sex was performed to interpret the associations

Comparisons Posterior Beta of (2(−ddct))ʎ SE Adjusted P-valuea 95% Credible Intervals for Beta
SNHG6
Total Patients vs. healthy subjects 1.299 0.2  < 0.0001 [0.89, 1.7]
Females vs. Males 0.016 0.08 0.736 [-0.14, 0.18]
Age (years) -0.001 0.003  > 0.999 [-0.01, 0.005]
Group a Sex -0.539 0.13 0.04 [-0.78, -0.29]
Male Patients vs. healthy subjects 0.772 0.1  < 0.0001 [0.58, 0.98]
Age -0.001 0.004 0.972 [-0.01, 0.01]
Female Patients vs. healthy subjects 0.223 0.1 0.023 [0.04, 0.43]
Age -0.001 0.005 0.967 [-0.01, 0.01]
CYP27B1
Total Patients vs. healthy subjects 0.415 0.07  < 0.0001 [0.28, 0.56]
Females vs. Males 0.083 0.07 0.08 [-0.05, 0.21]
Age (years) 0.003 0.003 0.19 [-0.002, 0.01]
Group a Sex -0.289 0.12 0.046 [-0.52, -0.06]
Male Patients vs. healthy subjects 0.404 0.06  < 0.0001 [0.28, 0.53]
Age 0.002 0.003 0.717 [-0.01, 0.01]
Female Patients vs. healthy subjects 0.189 0.1 0.419 [-0.05, 0.36]
Age 0.0001 0.006 0.178 [-0.01, 0.02]
MALAT1
Total Patients vs. healthy subjects 0.694 0.1  < 0.0001 [0.5, 0.88]
Females vs. Males -0.019 0.08 0.624 [-0.18, 0.14]
Age (years) -0.003 0.003 0.294 [-0.01, 0.004]
Group a Sex -0.501 0.14 0.021 [-0.77, -0.23]
Male Patients vs. healthy subjects 0.712 0.1  < 0.0001 [0.52, 0.9]
Age -0.002 0.004 0.439 [-0.01, 0.01]
Female Patients vs. healthy subjects 0.186 0.13 0.096 [-0.07, 0.44]
Age -0.003 0.007 0.541 [-0.02, 0.01]
Linc00346
Total Patients vs. healthy subjects 0.4 0.09 0.012 [0.21, 0.56]
Females vs. Males -0.041 0.07 0.078 [-0.17, 0.1]
Age (years) 0.003 0.001 0.588 [-0.003, 0.01]
Group a Sex -0.251 0.12 0.012 [-0.48, -0.02]
Male Patients vs. healthy subjects 0.41 0.08 0.038 [0.23, 0.56]
Age 0.007 0.001 0.238 [-0.003, 0.02]
Female Patients vs. healthy subjects 0.147 0.08 0.17 [-0.01, 0.3]
Age 0.002 0.001 0.695 [-0.01, 0.01]
VDR
Total Patients vs. healthy subjects 0.683 0.21 0.001 [0.29, 1.1]
Females vs. Males -0.088 0.12 0.292 [-0.33, 0.17]
Age (years) -0.006 0.01 0.596 [-0.02, 0.01]
Group a Sex -0.45 0.24 0.16 [-0.93, 0.004]
Linc00511
Total Patients vs. healthy subjects 0.019 0.08 0.920 [-0.13, 0.18]
Females vs. Males 0.015 0.1 0.175 [-0.18, 0.22]
Age (years) 0.007 0.001 0.006 [0.001, 0.01]
Group a Sex 0.088 0.13 0.658 [-0.17, 0.34]

aEstimated from frequentist methods, ʎ: Power transformation value estimated from Box-cox or Yeo-Johnson methods