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. 2021 Feb 23;26(6):1806–1816. doi: 10.1111/jcmm.16166

FIGURE 2.

FIGURE 2

Circ_0002137 inhibition retrained the proliferation of OS cell lines. A, Cell proliferation was detected using CCK8 assay on OS cell lines U2OS and MG‐63 after transfected with si‐circ0002137, ***P < .001. B‐C, Cell cycle arrested was observed using flow cytometry. Si‐circ0002137 group exhibited G0/G1 arrested compared with si‐NC group. ***P < .001, *P < .05. D, Cell apoptosis were determined through staining apoptotic cells with Annexin V‐FITC and PI, ***P < .001