FIGURE 1.

Circ_0008305 were up‐regulated in HCC. A, The expression of circ_0008305 was detected by real‐time PCR in HCC carcinoma and normal adjacent tissues. GAPDH was used as internal control. B, Comparison of low and high expression of circ_0008305 in HCC. C, Expression of circ_0008305 in HCC tissues at different stages. D, The expression level of circ_0008305 in HCC cells (SK‐HEP‐1, Huh‐7, Hep‐3B, HepG2 and SMMCC7721) and LO2 cells. Three independent experiments were carried out. Error bars stand for the mean ± SD of at least triplicate assays. **P < .01; ***P < .001