TABLE 2.
The relationship between the expression of circ_0008305 and the clinical characteristics of HCC patients
| Parameters | Patient number | Circ_0008305 | P value | |
|---|---|---|---|---|
| Low | High | |||
| expression (<median) | expression (≥ median) | |||
| All cases | 60 | 30 | 30 | |
| Age, years | ||||
| <60 | 33 | 16 | 17 | .435 |
| ≥60 | 27 | 12 | 15 | |
| Gender | ||||
| Male | 36 | 21 | 15 | .589 |
| Female | 24 | 17 | 7 | |
| Differentiation grade | ||||
| Well | 22 | 13 | 9 | .021 |
| Moderate | 21 | 15 | 6 | |
| Poorly | 17 | 6 | 11 | |
| Tumour size (cm) | ||||
| ≤5 | 34 | 19 | 15 | .003 |
| >5 | 26 | 14 | 12 | |
| Tumour capsular | ||||
| Incomplete | 24 | 9 | 15 | .016 |
| Complete | 36 | 12 | 24 | |
| TNM stage (I:II:III) | ||||
| I | 8 | 3 | 5 | .001 |
| II | 10 | 6 | 4 | |
| III | 42 | 12 | 30 | |
| Metastasis | ||||
| Yes | 22 | 5 | 17 | .000 |
| No | 48 | 12 | 36 | |
Data from 60 pairs tissue samples of HCC patients were analysed. The median expression level of circ_0008305 served as the cut‐off.
Numbers in bold indicate statistically significant.