Table 1.

Demographics and disease presentation of myeloid neoplasms with DNMT3A (R882 vs. Non-R882) mutations.

	DNMT3A R882 (Total = 36)	DNMT3A non-R882 (Total = 43)	P value*
Average age (Range)	66 (40–91)	72 (47-86)	NS
Gender
Male	21	17	NS
Female	15	26
Disease at presentation
AML (total 40)	27 (67.5%)	13 (32.5%)	0.0003
MDS (total 28)	7 (25%)	21 (75%)	0.009
MDS/MPN (total 3)	1 (33.5%)	2 (66.5%)	NS
MPN (total 8)	1 (12.5%)	7 (87.5%)	0.06

*T-test for age, and Fisher’s exact test for others.

NS, not significant; AML, Acute myeloid leukemia; MDS, Myelodysplastic syndrome; MPN, Myeloproliferative neoplasm.