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. 2022 Feb 28;13:845011. doi: 10.3389/fimmu.2022.845011

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Copyright © 2022 Zhou, Lin, Liu, Ding, Ma, Li, Xie, Lan and Feng

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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A. cantonensis infection caused activation of A1 and A2 astrocytes in the corpus callosum. (A, B) Representative sections showing that distribution of GFAP⁺, C3d⁺ and GFAP⁺, S100α10⁺ cells in the corpus callosum. (C) Quantification of GFAP⁺, C3d⁺ and GFAP⁺, S100α10⁺ cells at 7, 14, and 21 dpi. Scale bar = 50 μm. n = 4-5 animals/group, *P < 0.05, ***P < 0.001. Data were analyzed by one-way ANOVA and followed by Tukey’s post hoc analysis. Data in each statistical graph are presented as the mean ± SEM.