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. 2022 Feb 28;13:845011. doi: 10.3389/fimmu.2022.845011

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Copyright © 2022 Zhou, Lin, Liu, Ding, Ma, Li, Xie, Lan and Feng

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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IL-17A activated astrocytes in vitro. (A) Representative images display the expression of GFAP, C3d, and S100α10 in the presence of different concentration of IL-17A (UN=untreated). Scale bar = 75 μm. (B) Quantification of GFAP⁺, C3d⁺, and GFAP⁺ S100α10 cells of each treated group. n = 3/group, **P < 0.01, ***P < 0.001. Data were analyzed by one-way ANOVA and followed by Tukey’s post hoc analysis. Data in each statistical graph are presented as the mean ± SEM.