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. 2022 Feb 28;10:853754. doi: 10.3389/fped.2022.853754

Table 3.

Manometry findings before and after eosinophilic esophagitis treatment.

References N Treatment Manometric findings before treatment Manometric findings after treatment
Landres et al. (23) 1 Myotomy Vigorous achalasia Normalised peristalsis and LES pressure
Hempel (52) 1 Systemic steroids Low LES and DES Low LES; normalised peristalsis
Lucendo (43) 1 Fluticasone Hypomotility 80% normalised
Lucendo (44) 12 Fluticasone High amplitude contractions in 3, severe abnormal peristalsis and 1 with mildly abnormal peristalsis 7 had ongoing manometric abnormalities but all improved
Nennstiel (30) 20 Budesonide Early pan-esophageal pressurisation 3 (15%) Compartmentalised esophageal pressurisations 1 (5%) Frequently failed peristalsis 1 (5%) Weak peristalsis 2 (10%) Elevated IBP in 20% Reduction of IBP in 55% of patients
Resolution in 6/7 patients with manometric findings
(no improvement in frequently failed peristalsis)
Tanaka (53) 1 Systemic steroids
Myotomy
Jackhammer esophagus No change after steroids; resolution after myotomy
Funaki (54) 3 Systemic steroids Jackhammer esophagus All normalised

LES, Lower esophageal sphincter pressure; DES, Distal esophageal spasm; IBP, Intrabolus pressure.