Table 3.
Manometry findings before and after eosinophilic esophagitis treatment.
| References | N | Treatment | Manometric findings before treatment | Manometric findings after treatment |
|---|---|---|---|---|
| Landres et al. (23) | 1 | Myotomy | Vigorous achalasia | Normalised peristalsis and LES pressure |
| Hempel (52) | 1 | Systemic steroids | Low LES and DES | Low LES; normalised peristalsis |
| Lucendo (43) | 1 | Fluticasone | Hypomotility | 80% normalised |
| Lucendo (44) | 12 | Fluticasone | High amplitude contractions in 3, severe abnormal peristalsis and 1 with mildly abnormal peristalsis | 7 had ongoing manometric abnormalities but all improved |
| Nennstiel (30) | 20 | Budesonide | Early pan-esophageal pressurisation 3 (15%) Compartmentalised esophageal pressurisations 1 (5%) Frequently failed peristalsis 1 (5%) Weak peristalsis 2 (10%) Elevated IBP in 20% | Reduction of IBP in 55% of patients Resolution in 6/7 patients with manometric findings (no improvement in frequently failed peristalsis) |
| Tanaka (53) | 1 | Systemic steroids Myotomy |
Jackhammer esophagus | No change after steroids; resolution after myotomy |
| Funaki (54) | 3 | Systemic steroids | Jackhammer esophagus | All normalised |
LES, Lower esophageal sphincter pressure; DES, Distal esophageal spasm; IBP, Intrabolus pressure.