Table 3.
Univariate and multivariate analyses of factors influencing OS, after propensity score matching.
| Variables | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| χ2 | p-Value | HR (95% CI) | p-Value | |
| Age | ||||
| <65 or ≥65 years | 4.367 | 0.037 | 1.576 (0.979–2.536) | 0.061 |
| Sex | ||||
| Female or Male | 0.002 | 0.966 | ||
| Smoking index | ||||
| <400 or ≥400 | 0.413 | 0.520 | ||
| KPS | ||||
| <80 or ≥80 | 0.199 | 0.656 | ||
| Clinical stage | ||||
| I/II or III | 13.210 | <0.001 | 1.997 (1.340–2.976) | 0.001 |
| Obstructive pneumonia | ||||
| Yes or no | 0.784 | 0.376 | ||
| Initial treatment | ||||
| Concurrent CRT or sequential CRT | 0.076 | 0.783 | ||
| Response to initial treatment | ||||
| CR or PR/SD | 5.391 | 0.020 | 1.546 (0.916–2.608) | 0.103 |
| PCI | ||||
| Yes or no | 2.319 | 0.128 | 0.760 (0.533–1.083) | 0.129 |
OS, overall survival; HR, hazard ratio; CI, confidence interval; PCI, prophylactic cranial irradiation; KPS, Karnofsky Performance Status; CRT, chemoradiotherapy; CR, complete response; PR, partial response; SD, stable disease.
The bold values inidicate p-value is less than 0.05.