Table 4.
Univariate and multivariate analyses of factors influencing PFS, after propensity score matching.
| Variables | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| χ2 | p-Value | HR (95% CI) | p-Value | |
| Age | ||||
| <65 or ≥65 years | 4.579 | 0.032 | 1.578 (1.000–2.490) | 0.050 |
| Sex | ||||
| Female or Male | 0.122 | 0.727 | ||
| Smoking index | ||||
| <400 or ≥400 | 0.904 | 0.342 | ||
| KPS | ||||
| <80 or ≥80 | 0.002 | 0.960 | ||
| Clinical stage | ||||
| I/II or III | 11.716 | 0.001 | 1.806 (1.214–2.686) | 0.004 |
| Obstructive pneumonia | ||||
| Yes or no | 2.639 | 0.104 | ||
| Initial treatment | ||||
| Concurrent CRT or Sequential CRT | 1.281 | 0.258 | ||
| Response to initial treatment | ||||
| CR or PR/SD | 5.018 | 0.025 | 1.494 (0.900–2.479) | 0.120 |
| PCI | ||||
| Yes or no | 1.752 | 0.186 | 0.815 (0.579–1.147) | 0.241 |
OS, overall survival; HR, hazard ratio; CI, confidence interval; PCI, prophylactic cranial irradiation; KPS, Karnofsky Performance Status; CRT, chemoradiotherapy; CR, complete response;PR, partial response; SD, stable disease.
The bold values inidicate p-value is less than 0.05.