TABLE 5.
FDB and non-FDB patients and effect of treatment on lipid levels.
| Parameter | FDB | Baseline | Follow-up | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| N | Mean ± SD | p | N | Mean ± SD | p | N | Diference (%) | p | ||
| LDL-C (mmol/L) | + | 148 | 5.57 ± 1.46 | p < 0.001 | 124 | 3.45 ± 0.24 | p = 0.117 | 120 | −37.7 | p < 0.001 |
| − | 812 | 6.61 ± 1.95 | 779 | 3.21 ± 1.60 | 754 | −51.1 | ||||
| TC (mmol/L) | + | 153 | 7.88 ± 1.58 | p < 0.001 | 131 | 5.58 ± 1.37 | p = 0.252 | 131 | −30.3 | p < 0.001 |
| − | 840 | 9.09 ± 1.97 | 795 | 5.39 ± 1.72 | 795 | −40.7 | ||||
| APOB (g/L) | + | 85 | 1.53 ± 0.37 | p < 0.001 | 43 | 1.13 ± 0.38 | p = 0.448 | 26 | −29.2 | p = 0.023 |
| − | 430 | 1.83 ± 0.56 | 255 | 1.07 ± 0.51 | 132 | −40.7 | ||||
| TG (mmol/L) | + | 152 | 1.40 ± 0.98 | p < 0.001 | 131 | 1.07 ± 0.51 | p < 0.001 | 130 | −24.0 | p = 0.251 |
| − | 833 | 1.86 ± 1.17 | 795 | 1.42 ± 0.83 | 788 | −24.4 | ||||
| HDL-C (mmol/L) | + | 151 | 1.68 ± 0.47 | p = 0.960 | 129 | 1.60 ± 0.46 | p = 0.316 | 127 | −5.9 | p = 0.455 |
| − | 831 | 1.68 ± 0.46 | 790 | 1.55 ± 0.47 | 781 | −7.6 | ||||
| Lp(a) (g/L) | + | 133 | 0.40 ± 0.45 | p = 0.229 | 33 | 0.65 ± 0.62 | p = 0.350 | 33 | 61.2 | p < 0.001 |
| − | 715 | 0.46 ± 0.60 | 217 | 0.54 ± 0.66 | 216 | 1.0 | ||||
+, FDB; −, non-FDB; N – number of patients; SD, standard deviation; p, p-value.