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. 2022 Feb 28;9:856064. doi: 10.3389/fmolb.2022.856064

TABLE 2.

The correlations between nutritional parameters/blood parameters and SIRI.

Parameters N SIRI 785 N SIRI 477 N SIRI 308
Cases (n) 785 Low SIRI 484 High SIRI 301 χ2 p value Low SIRI 267 High SIRI 210 χ2 p value Low SIRI 217 High SIRI 91 χ2 p value
ALT (U/L) 0.820 0.365 0.071 0.791 1.699 0.192
 <15 370 (47.13%) 234 (48.35%) 136 (45.18%) 208 (43.61%) 115 (43.07%) 93 (44.29%) 162 (52.60%) 119 (54.84%) 43 (47.25%)
 ≥15 416 (52.99%) 250 (51.65%) 166 (55.15%) 269 (56.39%) 152 (56.93%) 117 (55.71%) 147 (47.73%) 98 (45.16%) 49 (53.85%)
AST (U/L) 0.092 0.762 0.153 0.696 0.444 0.505
 <18 378 (48.15%) 231 (47.73%) 147 (48.84%) 211 (44.23%) 116 (43.45%) 95 (45.24%) 167 (54.22%) 115 (53.00%) 52 (57.14%)
 ≥18 407 (51.85%) 253 (52.27%) 154 (51.16%) 266 (55.77%) 151 (56.55%) 115 (54.76%) 141 (45.78%) 102 (47.00%) 39 (42.86%)
LDH (U/L) 4.337 0.037 3.509 0.061 0.056 0.813
 <167 376 (47.90%) 246 (50.83%) 130 (43.19%) 193 (40.46%) 118 (44.19%) 75 (35.71%) 183 (59.42%) 128 (58.99%) 55(60.44%)
 ≥167 409 (52.10%) 238 (49.17%) 171 (56.81%) 284 (59.54%) 149 (55.81%) 135 (64.29%) 125 (40.58%) 89 (41.01%) 36 (39.56%)
GGT (U/L) 2.314 0.128 1.413 0.235 0.084 0.772
 <17 366 (46.62%) 236 (48.76%) 130 (43.19%) 203 (42.56%) 120 (44.94%) 83 (39.52%) 163 (52.92%) 116 (53.46%) 47 (51.65%)
 ≥17 419 (53.38%) 248 (51.24%) 171 (56.81%) 274 (57.44%) 147 (55.06%) 127 (60.48%) 145 (47.08%) 101 (46.54%) 44 (48.35%)
ALP (U/L) 0.273 0.601 2.149 0.143 1.369 0.242
 <64 377 (48.03%) 236 (48.76%) 141 (46.84%) 227 (47.59%) 135 (50.56%) 92 (43.81%) 150 (48.70%) 101 (46.54%) 49 (53.85%)
 ≥64 408 (51.97%) 248 (51.24%) 160 (53.16%) 250 (52.41%) 132 (49.44%) 118 (56.19%) 158 (51.30%) 116 (53.46%) 42 (46.15%)
GLU (mmol/L) 0.093 0.761 0.002 0.962 0.013 0.909
 <5.33 391 (49.81%) 239 (49.38%) 152 (50.50%) 247 (51.78%) 138 (51.69%) 109 (51.90%) 144 (46.75%) 101 (46.54%) 43 (47.25%)
 ≥5.33 394 (50.19%) 245 (50.62%) 149 (49.50%) 230 (48.22%) 129 (48.31%) 101 (48.10%) 164 (53.25%) 116 (53.46%) 48 (52.75%)
ALB (g/L) 3.817 0.051 0.007 0.933 9.576 0.002
 <45.2 392 (49.94%) 255 (52.69%) 137 (45.51%) 235 (49.27%) 132 (49.44%) 103 (49.05%) 157 (50.97%) 123 (56.68%) 34 (37.36%)
 ≥45.2 393 (50.06%) 229 (47.31%) 164 (54.49%) 242 (50.73%) 135 (50.56%) 107 (50.95%) 151 (49.03%) 94 (43.32%) 57 (62.64%)
CRP (mg/dl) 17.198 <0.0001 2.475 0.116 11.798 0.001
 <0.02 384 (48.92%) 265 (54.75%) 119 (39.53%) 187 (39.20%) 113 (42.32%) 74 (35.24%) 197 (63.96%) 152 (70.05%) 45 (49.45%)
 ≥0.02 401 (51.08%) 219 (45.25%) 182 (60.47%) 290 (60.80%) 154 (57.68%) 136 (64.76%) 111 (36.04%) 65 (29.95%) 46 (50.55%)
CA125 (U/ml) 5.051 0.025 2.956 0.086 0.784 0.376
 <13.35 392 (49.94%) 257 (53.10%) 135 (44.85%) 221 (46.33%) 133 (49.81%) 88 (41.90%) 171 (55.52%) 124 (57.14%) 47 (51.65%)
 ≥13.35 393 (50.06%) 227 (46.90%) 166 (55.15%) 256 (53.67%) 134 (50.19%) 122 (58.10%) 137 (44.48%) 93 (42.86%) 44 (48.35%)
CA153 (U/ml) 0.236 0.627 0.723 0.395 2.060 0.151
 <11.63 392 (49.94%) 245 (50.62%) 147 (48.84%) 208 (43.61%) 121 (45.32%) 87 (41.43%) 184 (59.74%) 124 (57.14%) 60 (65.93%)
 ≥11.63 393 (50.06%) 239 (49.38%) 154 (51.16%) 269 (56.39%) 146 (54.68%) 123 (58.57%) 124 (40.26%) 93 (42.86%) 31 (34.07%)
CEA (ng/ml) 2.025 0.155 2.025 0.155 2.174 0.140
 <1.66 392 (49.94%) 232 (47.93%) 160 (53.16%) 212 (44.44%) 111 (41.57%) 101 (48.10%) 180 (58.44%) 121 (55.76%) 59 (64.84%)
 ≥1.66 393 (50.06%) 252 (52.07%) 141 (46.84%) 265 (55.56%) 156 (58.43%) 109 (51.90%) 128 (41.56%) 96 (44.24%) 32 (35.16%)
D-D (mg/L) 0.147 0.702 0.039 0.844 5.007 0.025
 <0.29 387 (49.30%) 236 (48.76%) 151 (50.17%) 200 (41.93%) 113 (42.32%) 87 (41.43%) 187 (60.71%) 123 (56.68%) 64 (70.33%)
 ≥0.29 398 (50.70%) 248 (51.24%) 150 (49.83%) 277 (58.07%) 154 (57.68%) 123 (58.57%) 121 (39.29%) 94 (43.32%) 27 (29.67%)
FIB (g/L) 14.320 0.0002 11.241 0.001 1.468 0.226
 <2.85 388 (49.43%) 265 (54.75%) 123 (40.86%) 216 (45.28%) 139 (52.06%) 77 (36.67%) 172 (55.84%) 126 (58.06%) 46 (50.55%)
 ≥2.85 397 (50.57%) 219 (45.25%) 178 (59.14%) 261 (54.72%) 128 (47.94%) 133 (63.33%) 136 (44.16%) 91 (41.94%) 45 (49.45%)
INR 4.218 0.040 0.884 0.347 0.425 0.515
 <0.93 365 (46.50%) 239 (49.38%) 126 (41.86%) 177 (37.11%) 104 (38.95%) 73 (34.76%) 188 (61.04%) 135 (62.21%) 53 (58.24%)
 ≥0.93 420 (53.50%) 245 (50.62%) 175 (58.14%) 300 (62.89%) 163 (61.05%) 137 (65.24%) 120 (38.96%) 82 (37.79%) 38 (41.76%)
FDP (ug/ml) 4.691 0.030 0.300 0.584 2.025 0.155
 <1.40 367 (46.75%) 241 (49.79%) 126 (41.86%) 137 (28.72%) 74 (27.72%) 63 (30.00%) 230 (74.68%) 167 (76.96%) 63 (69.23%)
 ≥1.40 418 (53.25%) 243 (50.21%) 175 (58.14%) 340 (71.28%) 193 (72.28%) 147 (70.00%) 78 (25.32%) 50 (23.04%) 28 (30.77%)
White blood cell (W) (×109/L) 75.436 <0.0001 57.819 <0.0001 20.949 <0.0001
 <6.01 389 (49.55%) 299 (61.78%) 90 (29.90%) 239 (50.10%) 175 (65.54%) 64 (30.48%) 150 (48.70%) 124 (57.14%) 26 (28.57%)
 ≥6.01 396 (50.45%) 185 (38.22%) 211 (70.10%) 238 (49.90%) 92 (34.46%) 146 (69.52%) 158 (51.30%) 93 (42.86%) 65 (71.43%)
Red blood cell (R) (×1012/L) 7.107 0.008 5.283 0.022 1.887 0.170
 <4.40 389 (49.55%) 258 (53.31%) 131 (43.52%) 235 (49.27%) 144 (53.93%) 91 (43.33%) 154 (50.00%) 114 (52.53%) 40 (43.96%)
 ≥4.40 396 (50.45%) 226 (46.69%) 170 (56.48%) 242 (50.73%) 123 (46.07%) 119 (56.67%) 154 (50.00%) 103 (47.47%) 51 (56.04%)
Hemoglobin (Hb) (×109/L) 7.361 0.007 4.887 0.027 4.100 0.043
 <132 382 (48.66%) 254 (52.48%) 128 (42.52%) 243 (50.94%) 148 (55.43%) 95 (45.24%) 139 (45.13%) 106 (48.85%) 33 (36.26%)
 ≥132 403 (51.34%) 230 (47.52%) 173 (57.48%) 234 (49.06%) 119 (44.57%) 115 (54.76%) 169 (54.87%) 111 (51.15%) 58 (63.74%)
Neutrophil (N) (×109/L) 142.491 <0.0001 98.716 <0.0001 42.839 <0.0001
 <3.68 392 (49.94%) 323 (66.74%) 69 (22.92%) 229 (48.01%) 182 (68.16%) 47 (22.38%) 163 (52.92%) 141 (64.98%) 22 (24.18%)
 ≥3.68 393 (50.06%) 161 (33.26%) 232 (77.08%) 248 (51.99%) 85 (31.84%) 163 (77.62%) 145 (47.08%) 76 (35.02%) 69 (75.82%)
Lymphocyte (L) (×109/L) 7.843 0.005 1.884 0.170 4.817 0.028
 <1.76 391 (49.81%) 222 (45.87%) 169 (56.15%) 258 (54.09%) 137 (51.31%) 121 (57.62%) 133 (43.18%) 85 (39.17%) 48 (52.75%)
 ≥1.76 394 (50.19%) 262 (54.13%) 132 (43.85%) 219 (45.91%) 130 (48.69%) 89 (42.38%) 175 (56.82%) 132 (60.83%) 43 (47.25%)
Monocyte (M) (×109/L) 124.109 <0.0001 100.469 <0.0001 26.521 <0.0001
 <0.35 367 (46.75%) 302 (62.40%) 65 (21.59%) 216 (45.28%) 175 (65.54%) 41 (19.52%) 151 (49.03%) 127 (58.53%) 24 (26.37%)
 ≥0.35 418 (53.25%) 182 (37.60%) 236 (78.41%) 261 (54.72%) 92 (34.46%) 169 (80.48%) 157 (50.97%) 90 (41.47%) 67 (73.63%)
Eosinophils (E) (×109/L) 3.395 0.065 0.041 0.839 6.697 0.010
 <0.06 356 (45.35%) 207 (42.77%) 149 (49.50%) 241 (50.52%) 136 (50.94%) 105 (50.00%) 115 (37.34%) 71 (32.72%) 44 (48.35%)
 ≥0.06 429 (54.65%) 277 (57.23%) 152 (50.50%) 236 (49.48%) 131 (49.06%) 105 (50.00%) 193 (62.66%) 146 (67.28%) 47 (51.65%)
Basophils (B) (×109/L) 9.429 0.002 2.588 0.108 9.248 0.002
 <0.02 224 (28.54%) 157 (32.44%) 67 (22.26%) 136 (28.51%) 84 (31.46%) 52 (24.76%) 88 (28.57%) 73 (33.64%) 15 (16.48%)
 ≥0.02 561 (71.46%) 327 (67.56%) 234 (77.74%) 341 (71.49%) 183 (68.54%) 158 (75.24%) 220 (71.43%) 144 (66.36%) 76 (83.52%)
Platelet (P) (×109/L) 13.231 0.0003 8.329 0.004 3.482 0.062
 <243 388 (49.43%) 264 (54.55%) 124 (41.20%) 224 (46.96%) 141 (52.81%) 83 (39.52%) 164 (53.25%) 123 (56.68%) 41 (45.05%)
 ≥243 397 (50.57%) 220 (45.45%) 177 (58.80%) 253 (53.04%) 126 (47.19%) 127 (60.48%) 144 (46.75%) 94 (43.32%) 50 (54.95%)