Table 2.

Association between fitness status and angiotensin-converting enzyme-insertion/deletion (ACE-I/D) genotype on parameters of muscle oxygen kinetics during the ramp test of cycling exercise.

Phase	Parameter	Statistical size	Fitness	Genotype	Fitness × genotype	Muscle	Muscle × fitness	Muscle × genotype	Fitness × genotype
Rest	SmO2baseline	p-value	0.018	0.027	0.151	0.004	0.355	0.812	0.305
		η2	0.090	0.079	0.034	0.123	0.014	0.001	0.018
Exercise	SmO2min	p-value	≤ 0.001	0.597	0.098	0.052	0.208	0.031	0.296
		η2	0.240	0.005	0.045	0.058	0.026	0.075	0.018
Exercise	Δdeoxygenation	p-value	≤ 0.001	0.141	0.020	0.321	0.891	0.174	0.920
		η2	0.302	0.036	0.087	0.015	0.000	0.031	0.000
Exercise	tdeoxygenation	p-value	0.011	0.174	0.151	0.586	0.834	0.519	0.472
		η2	0.104	0.031	0.034	0.005	0.001	0.007	0.009
Exercise	Slopedeoxygenation	p-value	0.005	0.598	0.006	0.175	0.902	0.306	0.575
		η2	0.125	0.005	0.118	0.029	0.000	0.017	0.005
Stop	SmO2max	p-value	0.013	0.364	0.357	≤ 0.001	0.526	0.945	0.451
		η2	0.098	0.014	0.014	0.674	0.007	0.000	0.009
Stop	Δ1/2 reoxygenation	p-value	≤ 0.001	0.705	0.101	≤ 0.001	0.105	0.131	0.765
		η2	0.270	0.002	0.044	0.392	0.043	0.038	0.001
Stop	t1/2 reoxygenation	p-value	0.262	0.818	0.571	0.123	0.822	0.639	0.828
		η2	0.021	0.001	0.005	0.037	0.001	0.004	0.001
Stop	Slope1/2reoxygenation	p-value	0.031	0.598	0.365	0.823	0.682	0.607	0.592
		η2	0.076	0.005	0.014	0.001	0.003	0.004	0.005
Stop	SmO2overshoot	p-value	0.838	0.273	0.687	≤ 0.001	0.182	0.793	0.842
		η2	0.001	0.020	0.003	0.473	0.030	0.001	0.001

Values refer to the calculated level of statistical significance (p) and effect size (η²) for the effect of the aerobic fitness state, ACE-I/D genotype (ACE-II vs. ACE-ID/ACE-DD), and muscle type on assessed parameters of deoxygenation and reoxygenation in the leg muscles of the studied 34 subjects. P-values that were deemed statistically significant (i.e., p < 0.05) are underlined. ANOVA with post-hoc test of least significant difference.