Table 1.
N. | Sex, age (years) | Vaccine | Concomitant medications | Latency from the 1st dose (days) | Naranjo score# | Baseline BPDAI | Baseline ABSIS | Treatment | BPDAI at 3 months | ABSIS at 3 months |
---|---|---|---|---|---|---|---|---|---|---|
1 | F, 84 | Pfizer | Alendronate | 25 | 6 | 70 | 21 | Topical and systemic CS plus doxycycline | 0 | 0 |
2 | M, 83 | Pfizer | Allopurinol, amiodarone, amlodipine, bicalutamide, clonidine, furosemide, insulin, valsartan, warfarin | 32 | 6 | 50 | 18 | Topical and systemic CS plus doxycycline | 0 | 0 |
3 | F, 56 | Moderna | none | 7 | 6 | 17 | 4.5 | Topical CS plus doxycycline | 0 | 0 |
4 | M, 79 | Pfizer | ASA, amiodarone, atorvastatin, clopidogrel, hydrochlorothiazide, olmesartan, pantoprazole, tamsulosin | 4 | 6 | 23 | 10 | Topical CS plus doxycycline | 0 | 0 |
5 | M, 86 | Pfizer | Amiodarone, atorvastatin, clopidrogrel, domperidone, escitalopram, hydrochlorothiazide, levodopa/benserazide | 37 | 6 | 20 | 12 | Topical CS | 0 | 0 |
6 | M, 91 | Pfizer | Allopurinol, atorvastatin, furosemide, insulin, nebivolol | 28 | 6 | 80 | 30 | Topical and systemic CS | 0 | 0 |
7 | M, 86 | Pfizer | ASA, fenofibrate, isosorbide, ivabradine, pyridostigmine | 36 | 6 | 52 | 20 | Topical and systemic CS plus doxycycline | 0 | 0 |
8 | F, 84 | Moderna | Amlodipine, glimepiride, metformin, levothyroxine | 7 | 6 | 40 | 15 | Topical and systemic CS plus doxycycline | 0 | 0 |
9 | M, 84 | Pfizer | None | 23 | 6 | 37 | 54 | Systemic CS | 0 | 0 |
10 | F, 82 | Pfizer | None | 34 | 6 | 52 | 90 | Systemic CS | 6 | 27 |
11 | M, 76 | Pfizer | Candesartan, hydrochlorothiazide | 34 | 6 | 47 | 70 | Systemic CS | NA | NA |
12 | M, 78 | Pfizer | none | 4 | 4 | 42 | NA | Topical CS | 0 | NA |
13 | F, 90 | Pfizer | Allopurinol, hydrochlorothiazide, losartan | 28 | 4 | 142 | NA | Topical and systemic CS | 25 | NA |
14 | M, 90 | Pfizer | Alfuzosin, allopurinol, darbepoetin alfa, furosemide, levothyroxine, pregabalin, warfarin | 64 | 6 | 20 | NA | Systemic CS | 0 | NA |
15 | M, 72 | Pfizer | Insulin, telmisartan | 16 | 6 | 80 | NA | Topical and systemic CS plus MTX | 29 | NA |
16 | M, 80 | Pfizer | ASA, amlodipine, atenolol, atorvastatin, finasteride, salmeterol/fluticasone, zofenopril | 6 | 6 | 71 | 90 | Topical and systemic CS | 51 | 70 |
17 | F, 77 | AstraZeneca | Amlodipine, bisoprolol, furosemide, ramipril, sertraline | 3 | 8 | 42 | 60 | MTX | 0 | 0 |
18 | F, 60 | Pfizer | None | 75 | 6 | 10 | 36 | Systemic CS | 0 | 0 |
19 | F, 70 | Pfizer | None | 27 | 6 | 15 | 35 | Systemic CS | 1 | 5 |
20 | F, 72 | AstraZeneca (1st dose), Pfizer (2nd dose) |
ASA, amlodipine, levothyroxine, perindopril, simvastatin | 7 | 6 | 15 | NA | Systemic CS plus dapsone | 3 | NA |
21 | M, 85 | Pfizer | ASA, atenolol, dutasteride, indapamide, perindopril, tamsulosin | 27 | 6 | 15 | 30 | Systemic CS | 41 | 50 |
Naranjo scale interpretation: doubtful (≤0), possible (1-4), probable (5-8), definite (≥9).
CS, corticosteroids; MTX, methotrexate; NA, not available; ABSIS, Autoimmune Bullous Skin Disorder Intensity Score; ASA, acetylsalicylic acid; BPDAI, Bullous Pemphigoid Disease Area Index.