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. 2022 Mar 15;14(3):703–715. doi: 10.4251/wjgo.v14.i3.703

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©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/

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Texture analysis performed using contrast-free simulation computed tomography imaging. A: Target volumes delineation in a stereotactic ablative radiation therapy case. The high-dose planning target volume (blue) encompasses the tumour-vessel interface (TVI, encasement of celiac axis) inside the tumour planning target volume (PTVt, red). The prescription dose is 30 Gy and 50 Gy in 5 fractions, with simultaneous integrated boost, to PTVt and TVI, respectively. The following organ at risk are shown: duodenum (pink) and bowel (cyan); B: The gross tumour volume (GTV) of the pancreatic lesion without vessels (yellow) is shown in the same axial computed tomography (CT)-simulation image without contrast. This is the final CT used for analysis.