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. 2022 Feb 28;13:818122. doi: 10.3389/fphys.2022.818122

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Copyright © 2022 Stoyek, MacDonald, Mantifel, Baillie, Selig, Croll, Smith and Quinn.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Summary of the drivers of zebrafish sinoatrial node (SAN) automaticity. AP, action potential; DD, diastolic depolarisation; I_Ca,L, L-type Ca²⁺ current; I_Ca,T, T-type Ca²⁺ current; IBI, inter-beat interval; IBV, inter-beat variation; I_f, “funny” current; I_Kr/s, rapid/slow delayed rectifier K⁺ current; I_NCX, Na⁺-Ca²⁺ exchanger current; I_SAC,NS, cation non-selective stretch-activated channels; MDP, maximum diastolic potential; MSP, maximum systolic potential; RyR, ryanodine receptors; SR, sarcoplasmic reticulum; ZF, zebrafish.