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IC50 values for HDACs inhibition in HT-29 cells using class-distinguishing fluorogenic substrates whole-cell assay..
| |||
|---|---|---|---|
| # | R | Class-IIa (uM) | Class-I/IIb (uM) |
|
SAHA
TMP-195 |
|
>12.0
1.0 ± 0.20 |
0.95 ± 0.11
>50 |
| 6 |
|
>50 | >50 |
| 7 |
|
>50 | >50 |
| 8 |
|
>50 | >50 |
