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. Author manuscript; available in PMC: 2022 Mar 14.
Published in final edited form as: Eur J Med Chem. 2021 Dec 2;228:114011. doi: 10.1016/j.ejmech.2021.114011

Table 5.

IC50 values for HDACs inhibition in HT-29 cells (compounds 23–25)..

graphic file with name nihms-1774621-t0025.jpg
# R Class-IIa (nM) Class-I/IIb (nM)
20 CF2Cl >2000 >2000
21 CF2Br >5000 >5000