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. 2022 Feb 28;16:846584. doi: 10.3389/fnins.2022.846584

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Copyright © 2022 Zhao, Lv, Yang and Peng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The retinal morphology changes with time after tail vein injection of methyl methanesulfonate (MMS). (A) The Panorama of retina. (B) The main layers of retina. (C) The normal retina without MMS administration and the retina 1, 2, 3, 4, 5, and 7 days after MMS administration. The asterisk represents the posterior vacuole structure in RPE cells. (D) The histogram of the thickness of outer nucleus layer (ONL). One way ANOVA multiple comparisons was analyzed, ^∗∗∗∗P < 0.0001 for differences compared with controls; ^##P < 0.01, ^####P < 0.0001 for differences compared with previous time point group, n = 3.