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. 2022 Feb 28;16:846584. doi: 10.3389/fnins.2022.846584

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Copyright © 2022 Zhao, Lv, Yang and Peng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The retinal function deteriorates with time after tail vein injection of MMS. (A) The b-wave of Dark-adapted 0.01 electroretinogram (ERG) of normal retina without MMS treatment and retina after MMS administration (1, 3, 5, and 7 days). (B) The b-wave of Dark-adapted 3.0 ERG of normal retina without MMS treatment and retina after MMS administration (1, 3, 5, and 7 days). (C) The histogram of the amplitude of b-wave of Dark-adapted 0.01 ERG. One way ANOVA multiple comparisons was analyzed, ^∗∗∗∗P < 0.0001 for differences compared with controls, n = 3. (D) The histogram of the amplitude of b-wave of Dark-adapted 3.0 ERG. One way ANOVA multiple comparisons was analyzed, ^∗∗∗∗P < 0.0001 for differences compared with controls; ^####P < 0.0001, ^##P < 0.01 for differences compared with previous time point group, n = 3.