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. 2022 Mar 14;13(3):235. doi: 10.1038/s41419-022-04674-3

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — A Heatmap visualization of significantly differentially expressed proteins (DEPs) whose regulation concentrated on three enriched pathways. The graphs show the relative intensity of DEPs. Proteins included in the heatmap meet the requirement that fold-change >1.5 or <0.67 and p value (t test) of <0.05. p values were then adjusted using the Benjamini-Hochberg correction (false discovery rate, <0.05). The color bar represents the relative intensity of identified proteins from −6 to 6. B The boxplots show six proteins, which are significantly different between COVID-19 survivors 6 months after discharge and healthy control subjects. Healthy group, n = 30; non-severe group, n = 30; severe group, n = 24. APOD apolipoprotein D; APOM apolipoprotein M; C3 complement 3; FN1 fibronectin 1; NRP1 Neuropilin-1; TGFβ1 transforming growth factor beta 1.