TABLE 1.
Variable | Placebo (n = 10) | MCT oil (n = 10) | P‐values |
---|---|---|---|
Age (years) | 75.7 ± 8.8 (53‐84) | 68.4 ± 9.9 (56‐84) | .67 |
Sex (M:F) | 4:6 | 7:3 | .89 |
Height (in) | 64.7 ± 3.9 (59‐70) | 68.3 ± 4.6 (63‐78) | .07 |
Weight (lbs) | 171.9 ± 30.2 (133‐210) | 161.4 ± 31.8 (114‐220) | .82 |
BMI (kg/m2) | 28.5 ± 3.0 (24‐33) | 24.1 ± 3.5 (19‐30) | .73 |
Level of education (% college/university) | 50.0 | 90.0 | .49 |
APOE ε4 status | N = 10 | N = 9 | .27 |
Absent | 6 (60%) | 3 (33%) | .25 |
Heterozygote | 2 (20%) | 5 (56%) | .11 |
Homozygote | 2 (20%) | 1 (11%) | .60 |
AChEI use | 6 (60%) | 8 (80%) | .35 |
Memantine use | 2 (20%) | 2 (20%) | .82 |
Baseline MMSE | 23 (12–28) | 22.3 (10–29) | .79 |
Baseline MoCA | 15.9 (0–29) | 15.4 (4–27) | .65 |
Baseline Cog 1 | 88.5 (65–110) | 67.1 (0–106) | <.001* |
Baseline Cog 2 | 70.9 (0–102) | 61.7 (0–107) | .43 |
Note:
*Statistically significant difference.
Abbreviations: APOE, apolipoprotein E; BMI, body mass index; MCT, medium chain triglyceride; MMSE, Mini0‐Mental State Examination; MoCA, Montreal Cognitive Assessment.