Figure EV1. Clustering of p53 mRNA targets under oscillating and pulsatile p53 expression.

• A, B
  p53 target genes were clustered via fuzzy c‐means clustering according to their mRNA expression profiles under (A) oscillatory or (B) rising p53 expression. Differential mRNA expression was defined as fold change > 1.5 and FDR < 0.2 (t‐test, Benjamini–Hochberg corrected) based on two independent experiments. mRNAs were clustered based on their normalized time traces (z score) into five expression clusters under oscillatory and rising p53.