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. 2021 Jun 17;7(9):4102–4127. doi: 10.1021/acsbiomaterials.0c01784

Figure 6.

Figure 6

Example of HA hydrogels that encapsulate siRNA: (a) schematic of the siRNA-cholesterol interaction with cholesterol/CD interactions, (b) fluorescence recovery after photobleaching diffusivity with encapsulated fluorescein (FAM)-modified, with (+) and without (−) CD, (c) cumulative FAM-modified, cholesterol-modified siRNA release from hydrogels with or without CD, and (d) schematic of erosion and si-RNA response to delivery of active MMP. Reproduced and adapted with permission from ref (243). Copyright 2018, Elsevier.