Table 3.
Effects of demographic and clinical variables on latent profile classification: selected results of multinomial logit model1
| Covariate | Latent Profile | ||
|---|---|---|---|
| High Symptom SufferingOR (95% C.I.) | Medium Symptom SufferingOR (95% C.I.) | Low Symptom SufferingOR (95% C.I.) | |
| Age | 1.22 (1.05, 1.41) * | 1.14 (1.03, 1.26)* | - |
| Gender | |||
| Female | - | - | - |
| Male | 0.80 (0.34, 1.91) | 0.89 (0.45, 1.76) | |
| Parent Education | 0.79 (0.35, 1.81) | 0.73 (0.37, 1.46) | - |
| <College | - | - | |
| College+ | 0.79 (0.35, 1.81) | 0.73 (0.37, 1.46) | - |
| Race | |||
| Others | - | - | |
| White | 0.48 (0.19, 1.25) | 0.83 (0.35, 1.97) | - |
| Black | 0.57 (0.17, 1.99) | 0.64 (0.23, 1.75) | |
| Time since diagnosis | |||
| ≤ Median | - | - | |
| > Median | 1.03 (0.98, 1.08) | 1.03 (0.99, 1.06) | |
| Hemoglobin | 1.00 (0.77, 1.30) | 0.80 (0.64, 1.00) | - |
| Fatigue Severity2 | |||
| No | - | - | |
| Yes | 2.99 (1.08, 8.31) * | 11.37 (4.53, 28.58)* | - |
| Pain Severity2 | |||
| No | - | - | |
| Yes | 6.36 (2.64, 15.34) * | 2.59 (1.30, 5.15)* | - |
| Anxiety Severity2 | |||
| No | - | - | |
| Yes | 16.75 (6.36, 44.15) * | 3.67 (1.76, 7.68)* | - |
| Cancer Type | |||
| Neuro-oncology | - | - | |
| Leukemia/Lymphoma | 2.56 (0.56, 11.79) | 1.66 (0.64, 4.34) | |
| Solid tumor | 3.00 (0.62, 14.61) | 1.74 (0.62, 4.89) | |
Notes:
-Reference group
*
Statistically significant as α < 0.05
1
Estimated using 3-step method in Mplus 8.4
2
Ped-PRO-CTCAE severity experience at baseline (T1)