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7e·HCl (40 mg/kg/day) has oral efficacy in P. berghei-infected mice. A transgenic P. berghei ANKA strain (l676m1cl1 line, PbGFP-Luccon) was used, that expresses a fusion GFP (mutant 3) and firefly luciferase (LucIAV). CQ is chloroquine. Note: three of the five vehicle-treated mice died before Day 7.
