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. 2022 Mar;47(2):162–166. doi: 10.30476/IJMS.2022.92862.2415

Table 2.

Clinical data after COVID-19 infection and outcome of treatment strategy in 9 patients with primary immunodeficiency

ID Age (month) Sex PID diagnosis COVID-19 related symptoms Treatment strategy Medication Outcome/Cause of death
P1 5 F SCID Fever, Cough, Dyspnea, Respiratory distress Hospitalized IVIG, Acyclovir, Clindamycin, Meropenem, Fluconazole, Steroid Death/ARDS
P2 32 F CID-STIM1 deficiency Fever, Cough, Dyspnea, Respiratory distress, retraction, hypotension , tachypnea Hospitalized /ICU IVIG, Vancomycin, Meropenem, Piperacillin/tazobactam, steroid Death/Sepsis, Cardiorespiratory arrest
P3 18 M ICF syndrome Fever Hospitalized/ ICU IVIG, Acyclovir, Vancomycin, Piperacillin/tazobactam, steroid Recovery
P4 124 F Ataxia-telangiectasia - Hospitalized IVIG, Recovery
P5 22 M Bruton agammaglobulinemia Fever, Cough, Runny nose and sneezing, myalgia Hospitalized IVIG, Acyclovir, Vancomycin, Piperacillin/tazobactam, steroid Recovery
P6 27 M Bruton agammaglobulinemia Fever, Cough, Myalgia, Anosmia No IVIG, Azithromycin Recovery
P7 72 F CVID Fever, Cough, Dyspnea, GI symptom Hospitalized IVIG, Recovery
P8 480 F CVID Fever, Respiratory distress, GI symptom, Anosmia Hospitalized IVIG, Meropenem, Tocilizumab, Steroid, Ceftriaxone Recovery
P9 204 F Hyper IgE Fever, Respiratory distress Hospitalized, ICU IVIG, Cefixime, Cetirizine Death/ARDS

PID: Primary immunodeficiency; CID: Combined immunodeficiency; SCID: Severe combined immunodeficiency; ICF: Facial anomalies syndrome; CVID: Common variable immunodeficiency; IVIG: Intravenous immunoglobulin; ARDS: Acute respiratory distress syndrome; P: Patient; M: Male; F: Female