Table 1.
Baseline characteristics of study participants according to intervention groupa
| ICR (n = 49) | CCR (n = 46) | Control (n = 52) | pb | |
|---|---|---|---|---|
| Sex, n (%) | ||||
| Men, n (%) | 25 (51.0%) | 24 (52.2%) | 25 (48.1%) | |
| Women, n (%) | 24 (49.0%) | 22 (47.8%) | 27 (51.9%) | |
| Age, years | 49.4 ± 9.0 | 50.8 ± 7.8 | 50.6 ± 7.1 | 0.71 |
| Weight, kg | 96.4 ± 15.8 | 93.0 ± 16.0 | 93.3 ± 13.3 | 0.39 |
| BMI, kg/m2 | 32.0 ± 3.7 | 31.2 ± 3.9 | 31.1 ± 3.6 | 0.46 |
| Subcutaneous adipose tissue, cm3 | 12822 ± 4267 | 12167 ± 3985 | 11945 ± 3845 | 0.55 |
| Visceral adipose tissue, cm3 | 4818 ± 1889 | 5012 ± 2183 | 4943 ± 2267 | 0.96 |
| Systolic blood pressure, mmHg | 139.4 ± 18.7 | 136.3 ± 16.9 | 136.0 ± 12.5 | 0.47 |
| Diastolic blood pressure, mmHg | 87.2 ± 9.9 | 87.4 ± 8.6 | 87.8 ± 7.3 | 0.93 |
| Glucose, mg/dL | 92.7 ± 7.5 | 94.3 ± 7.6 | 93.5 ± 7.4 | 0.69 |
| HOMA-IR | 2.7 ± 1.3 | 3.0 ± 1.8 | 3.0 ± 1.8 | 0.58 |
| Triglycerides, mg/dL | 130.0 ± 83.8 | 122.5 ± 67.1 | 145.0 ± 85.5 | 0.31 |
| Cholesterol, mg/dL | 205.0 ± 30.8 | 204.6 ± 39.8 | 211.8 ± 36.1 | 0.42 |
an = 147. Values are means ± SD. ICR — Intermittent calorie restriction, CCR — Continuous calorie restriction
bANOVA comparison between intervention group for all variables except sex. p-value for sex is from chi-square test for the comparison of the distribution of sexes across intervention groups. Values are reported only for participants gut microbiota data at baseline