Table 5.
Liver function tests before and after BMMNCs administration
| Indicator | Baseline | 3 months | 6 months | 12 months |
|---|---|---|---|---|
| (N = 19) | (N = 19) | (N = 18) | (N = 18) | |
| Median [min; max] | Median [min; max] | Median [min; max] | Median [min; max] | |
| Serum Bilirubin (mg/dL) | 2.5 | 1.3 | 0.7 | 0.4 |
| [0.9; 7.0] | [0.3; 10.4] | [0.2; 5.7] | [0.2; 4.7] | |
| P = 0.77 | P = 0.02* | P = 0.026* | ||
| Alanine Aminotransferase (ALT) (U/L) | 86.9 | 87.0 | 103.5 | 47.8 |
| [18.8; 502.0] | [10.1; 265.2] | [16.6; 276.0] | [16.6; 876.0] | |
| P = 0.74 | P = 0.93 | P = 0.22 | ||
| Aspartate Aminotransferase (AST) (U/L) | 115.8 | 107.5 | 90.9 | 65.5 |
| [32.4; 954] | [31.4; 224.3] | [37.5; 276.5] | [37.5; 285] | |
| P = 0.154 | P = 0.79 | P = 0.08 | ||
| Gamma-Glutamyl Transferase (GGT) | 211.3 | 201.3 | 228.0 | 149.1 |
| [18.8; 502.0] | [10.1; 265.2] | [14.0; 556.5] | [14.0; 624.4] | |
| P = 0.06 | P = 0.39 | P = 0.005** | ||
| International Normalized Ratio (INR) | 1.06 | 1.05 | 1.03 | 1.05 |
| [0.9; 1.42] | [0.9; 1.37] | [0.8; 1.27] | [0.9; 1.26] | |
| P = 0.18 | P = 0.036* | P = 0.163 | ||
| Albumin (g/dL) | 3.8 | 3.9 | 4.1 | 3.8 |
| [2.7; 4.5] | [3.3; 4.5] | [3.1; 4.4] | [3.2; 4.1] | |
| P = 0.10 | P = 0.03* | P = 0.72 | ||
| Prothrombin Time (PT) (second) | 11.7 | 11.6 | 11.6 | 11.7 |
| [9.8; 18.0] | [10.4; 15.3] | [9.9; 15.4] | [10.3; 16.9] | |
| P = 0.32 | P = 0.35 | P = 0.61 |
*P value < 0.05; **P value < 0.01