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. Author manuscript; available in PMC: 2022 Mar 14.
Published in final edited form as: Environ Int. 2021 Aug 26;157:106822. doi: 10.1016/j.envint.2021.106822

Fig. 1.

Fig. 1.

Obesogenic phenotype in male mice ancestrally exposed to TBT. Weekly body weight and body composition in animals ancestrally exposed to 5 nM TBT (A, C) and 50 nM TBT (B, D) compared to control group (DMSO). (E) Percentage of body fat loss after ~16 h of fasting at 28 weeks of age. (F) Plasma levels of leptin at 28 weeks of age. Statistical significance was determined by two-way ANOVA followed by Dunnett’s post-test in panels A–D. Statistical significance was determined by Kruskal-Wallis test followed by Dunn’s post-test in panels E–F. Data are presented as mean ± s.e.m. *p < 0.05, **p < 0.01, #p < 0.001. BW: Body Weight; SD: Standard diet; HFD: Higher fat diet. Panels A–E: Control n = 17, TBT5 n = 16, TBT50 n = 16; for panel F: Control n = 12, TBT5 n = 16, TBT50 n = 11.