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. Author manuscript; available in PMC: 2022 Mar 14.
Published in final edited form as: Environ Int. 2021 Aug 26;157:106822. doi: 10.1016/j.envint.2021.106822

Fig. 4.

Fig. 4.

Two-dimensional PLS-DA scores plot of T3 study plasma samples integrated 1H NMR spectra at 8 weeks of age. Left column: Male samples; Right column: Female samples. Each dot represents an observation (animal), projected onto first (horizontal axis) and second (vertical axis) PLS-DA components. Groups are shown in different symbols and colors. The black ellipse determines the 95% confidence interval, which is drawn using Hotelling’s T2 statistic. A. All male samples (Control: n = 11, TBT5: n = 15, TBT50: n = 13, 1 latent component, R2Y = 46.3%, Q2 = 0.42). B. All female samples (Control: n = 13, TBT5: n = 13, TBT50: n = 13, no valid model). C. Control/TBT5 male samples (Control: n = 11, TBT5: n = 15, 2 latent components, R2Y = 90.6%, Q2 = 0.74). D. Control/TBT5 female samples (Control: n = 12, TBT5: n = 13, 2 latent components, R2Y = 98.4%, Q2 = 0.84). E. Control/TBT50 male samples (Control: n = 11, TBT50: n = 13, 2 latent components, R2Y = 98.2%, Q2 = 0.90). F. Control/TBT50 female samples (Control: n = 13, TBT50: n = 13, 2 latent components, R2Y = 95.9%, Q2 = 0.92).