Table 4.

Factors predictive of death in the multivariate analysis

Variablea	OR	95% CI	P-value
Hyperlactatemia (lactate > 5 µmol/L)	8.6	2.03–36.1	0.004
Jaundice or increased bilirubin (> 50 µmol/L)	5.1	1.49–17.30	0.009
Antibiotics before admissionb	0.1	0.02 –0.85	0.03
Yellow fever vaccination	0.2	0.05 – 0.79	0.02

OR odds ratio, CI confidence interval

^aAdjusted by center

^bBetween disease onset and admission