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. 2022;22(1):123–131.

Figure 1.

Figure 1

Overexpression of BMP-2 can promote osteogenic differentiation of MSCs. (A) The expression of BMP-2 in BMP-2 OE and KD groups were detected by Western blot. Histogram results in (A). *p<0.05 and **p<0.01 comparing to NC group. (B) The ALP activity in MSCs in differentiation days was detected. *p<0.05 comparing to value in NC group. (C) RT-qPCR was used to detect the mRNA expression of Runx2, Osterix, and OCN in MSCs at 14th day. **p<0.01 and ***p<0.001 comparing to NC group. (D) The expression of Runx2, Osterix, and OCN in MSCs in differentia-tion days was detected by Western blot. (E) Histogram summarizing results in (D). *p<0.05, **p<0.01 and ***p<0.001. Data are shown as mean ± SEM (n=3).