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. Author manuscript; available in PMC: 2022 Mar 14.
Published in final edited form as: Cancer Chemother Pharmacol. 2019 Jan 8;83(3):589–598. doi: 10.1007/s00280-019-03767-9

Table 3:

Treatment-related toxicity, arm by grade, n (%)

Adverse Event TREATMENT ARM BY GRADE, n(%)
Abraxane 35 mg/m2 (n=4) Abraxane 70 mg/m2 (n=4) Abraxane 90 mg/m2 (n=3) Abraxane 112.5 mg/m2 (n=6) Abraxane 140 mg/m2 (n=7) Abraxane 175 mg/m2 (n=3)
2 3 4 2 3 4 2 3 4 2 3 4 2 3 4 2 3 4
AST, SGOT 0 0 0 0 0 0 2(67%) 0 0 0 0 0 0 0 0 0 0 0
Albumin, serum-low 0 0 0 1(25%) 0 0 0 0 0 1(17%) 0 0 0 0 0 0 0 0
Alkaline phosphatase 0 0 0 0 0 0 0 1(33%) 0 1(17%) 0 0 0 0 0 0 0 0
Amylase 0 0 0 0 0 1(25%) 0 0 0 0 0 0 0 0 0 0 0 0
Anorexia 0 0 0 0 0 0 0 0 0 0 1(17%) 0 1(14%) 0 0 0 0 0
Diarrhea 0 0 0 1(25%) 0 0 0 0 0 0 0 0 1(14%) 0 0 0 0 0
Distension/bloating, abdominal 0 0 0 1(25%) 0 0 0 0 0 2(33%) 0 0 0 0 0 0 0 0
Fatigue 0 0 0 2(50%) 0 0 1(33%) 0 0 1(17%) 1(17%) 0 3(43%) 2(29%) 0 1(33%) 1(33%) 0
Glucose, serum-high 0 0 0 1(25%) 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Hair loss/alopecia 0 0 0 0 0 0 0 0 0 1(17%) 0 0 1(14%) 0 0 0 0 0
Hemoglobin 1(25%) 0 0 2(50%) 0 0 2(67%) 0 0 1(17%) 1(17%) 0 1(14%) 2(29%) 0 2(67%) 0 0
Infection 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1(33%) 0
Left ventricular systolic dysfunction 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1(33%) 0 0
Leukocytes 0 0 0 1(25%) 1(25%) 0 0 0 0 2(33%) 1(17%) 1(17%) 3(43%) 1(14%) 0 1(33%) 1(33%) 0
Lipase 0 0 0 0 0 1(25%) 0 0 0 0 0 0 0 0 0 0 0 0
Lymphopenia 0 0 0 0 0 2(50%) 1(33%) 0 0 0 2(33%) 0 0 2(29%) 0 0 0 0
Mucositis/stomatitis 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1(33%) 0 0
Neuropathy 0 0 0 0 0 0 0 0 0 0 0 0 1(14%) 0 0 0 0 0
Neutrophils/granulocytes 0 0 0 1(25%) 1(25%) 0 0 0 0 2(33%) 1(17%) 1(17%) 0 2(29%) 0 1(33%) 0 2(67%)
Pain 2(50%) 0 0 1(25%) 0 0 0 0 0 0 0 0 1(14%) 0 0 1(33%) 1(33%) 0
Pancreatitis 0 0 0 0 1(25%) 0 0 0 0 0 0 0 0 0 0 0 0 0
Phosphate, serum-low 0 0 0 1(25%) 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Platelets 0 0 0 0 0 0 0 0 0 0 0 1(17%) 0 0 0 0 0 0
Proteinuria 0 0 0 0 0 0 0 0 0 0 0 0 1(14%) 0 0 0 0 0
Rash/desquamation 0 0 0 0 1(25%) 0 0 0 0 0 0 0 0 0 0 0 0 0
Sodium, serum-low 0 0 0 0 0 0 0 0 0 0 1(17%) 0 0 0 0 0 0 0
Ulcer, GI 0 0 0 0 0 0 1(33%) 0 0 0 0 0 0 0 0 0 0 0
Vomiting 1(25%) 0 0 2(50%) 0 0 0 0 0 0 0 0 0 0 0 0 0 0