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Standard deviation scores (SDS) for cephalometric features of untreated isolated growth hormone deficiency (IGHD). Values lower than −2 or higher than +2 are by definition abnormal. (a) P < .001 in comparison with the other linear measurements. (b) P < .001 for both lower-anterior facial height and mandibular ramus height in comparison with other linear measurements. (c) P < .001 in comparison with the other angular measurements (analysis of variance [ANOVA] with the Tukey test).
